IL4 Receptor antibody (Extracellular Domain)

Catalog No. ABIN327343

Product Details anti-IL4 Receptor Antibody

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Binding Specificity: Extracellular Domain

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This IL4 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Specificity: Recognizes mouse IL-4 R extracellular domain. In direct ELISAs and Western Blots, this antibody shows less than 1 % cross-reactivity with rhIL-4 R, rhIL-9 R, rhIL-13 R 1 and rmIL-13 R 2.

Purification: Immunoaffinity purified

Immunogen: NS0-derived rmIL-4 R extracellular domain.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 1 μg/mL), Flo (3 - 10 μg/mL), WB (0.1 - 0.2 μg/mL)

Usage: Suitable for use in Western Blot, Direct ELISA and Flow Cytometry. Western Blot: 0.1-0.2 μg/mL Detection limit is ~0.5 ng/lane under non-reducing and reducing conditions. ELISA: 0.5-1 μg/mL Detection limit is ~0.2 ng/well. Flow Cytometry: 3-10 μg/mL/1 x10⁶.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitution: Reconstitute, sterile PBS. If 1 mL of PBS is used, the antibody concentration will be 100 μg/mL.

Concentration: Lot specific

Buffer: Lyophilized from PBS, 5 % trehalose. Reconstitution: Reconstitute, sterile PBS. If 1 mL of PBS is used, the antibody concentration will be 100 μg/mL.

Target Details for IL4 Receptor

Target: IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

Alternative Name: IL4R / CD124 (IL4R Products)

Background: Name/Gene ID: IL4R
Family: Interleukin

Synonyms: IL4R, CD124, CD124 antigen, IL-4RA, IL4R nirs variant 1, IL4RA, Interleukin 4 receptor, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha

Gene ID: 3566

UniProt: P24394

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process