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CD45 antibody

PTPRC Reactivity: Rat FACS, IP Host: Mouse Monoclonal OX-29 unconjugated
Catalog No. ABIN320193
  • Target See all CD45 (PTPRC) Antibodies
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    Reactivity
    • 328
    • 208
    • 75
    • 28
    • 20
    • 16
    • 15
    • 10
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    Rat
    Host
    • 230
    • 145
    • 143
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 381
    • 134
    • 1
    Monoclonal
    Conjugate
    • 163
    • 49
    • 41
    • 36
    • 34
    • 13
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    • 3
    • 3
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    This CD45 antibody is un-conjugated
    Application
    • 420
    • 175
    • 148
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    • 91
    • 58
    • 40
    • 37
    • 37
    • 27
    • 15
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificity
    This antibody is the equivalent of human CD45. SM2195P recognises a monomorphic determinant present on all forms of the L-CA (CD45) antigen. (1) Studies have demonstrated that this antibody binds to the membrane distal two domains of CD45.(3)
    Purification
    Affinity Chromatography on Protein G.
    Immunogen
    L-CA (CD45). Fusion of cells from NSO mouse myeloma line with spleen cells from BALB/c mice immunised with purified LCA.
    Clone
    OX-29
    Isotype
    IgG2a
    Top Product
    Discover our top product PTPRC Primary Antibody
  • Application Notes
    Flow Cytometry (1/10-1/50): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    Alternative Name
    CD45 / LCA (PTPRC Products)
    Synonyms
    PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody
    Background
    CD45 is a major membrane glycoprotein of 180kD on thymocytes and 180-240kD on other leucocytes.Synonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
    Gene ID
    24699
    NCBI Accession
    NP_001103357
    UniProt
    P04157
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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