CD16 antibody

Catalog No. ABIN320001

This anti-CD16 antibody is a Rat Monoclonal antibody detecting CD16 in FACS and IHC (fro). Suitable for Human.

Quick Overview for CD16 antibody (ABIN320001)

Target: CD16

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This CD16 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: YFC120-5

Product Details anti-CD16 Antibody

Specificity: This antibody binds specifically to the leucocyte low affinity Fc receptor (Fc RIII), also known as CD16. It recognises a 50-70 kDa leucocyte surface antigen.

Purification: Affinity chromatography on Protein A.

Immunogen: Human neutrophils. Spleen cells from Lou rat fused with the rat myeloma cell line. Y3/Ag.1.2.3.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background: The antigen is expressed by neutrophils, NK cells, K cells and a subpopulation of macrophages.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

Gene ID: 2214

NCBI Accession: NP_000560

UniProt: P08637

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process