CRLF2 antibody (Middle Region)

Catalog No. ABIN318884

Product Details anti-CRLF2 Antibody

Target: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognises thymic stromal lymphopoietin receptor (TSLPR).

Purification: Antisera to human TSLP receptor were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Immunogen: A 19 amino acid peptide located near the centre of human TSLP recptor.

Isotype: IgG

Application Details

Application Notes: Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 53 kDa in human liver tissuecell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for CRLF2

Target: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Alternative Name: CRLF2 (CRLF2 Products)

Background: TSLPR is a 42 kDa glycoprotein belonging to the type 1 cytokine receptor family. TSLPR is primarily expressed by dendritic cells and monocytes, and weakly expressed by T-cells. It is also expressed by non-haematopoietic tissues such as the heart, skeletal muscle, kidney and liver. The TSLP receptor forms functional complexes with thymic stromal lymphopoietin (TSLP) and IL-7R, which are capable of stimulating cell proliferation through activation of Stat3 and Stat5.Synonyms: Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL-XR, ILXR, TSLPR, Thymic stromal lymphopoietin protein receptor

Gene ID: 64109

NCBI Accession: NP_071431

UniProt: Q9HC73