TARDBP antibody (N-Term)
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- Target See all TARDBP Antibodies
- TARDBP (TAR DNA Binding Protein (TARDBP))
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Binding Specificity
- AA 1-260, N-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TARDBP antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- The antibody recognizes Human TARDBP. Other species not tested.
- Characteristics
- Synonyms: TDP43, TDP-43, TAR DNA-binding protein 43
- Purification
- Protein-G Affinity Chromatography
- Immunogen
- Recombinant Human TARDBP (1-260 aa) purified from E. coli.
- Clone
- K1B8
- Isotype
- IgG1
- Top Product
- Discover our top product TARDBP Primary Antibody
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anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP Reactivity: Human WB, ELISA, IF, IP, IHC (p), RNAi Host: Mouse Monoclonal 2E2-D3 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibodyTARDBP Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibodyTARDBP Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP Reactivity: Human WB, IHC, ELISA, ICC, FACS Host: Mouse Monoclonal 6G2D8 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibodyTARDBP Reactivity: Human WB, IP, RIP Host: Rabbit Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibodyTARDBP Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyKO Validated TARDBP Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibodyTARDBP Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-396) antibodyTARDBP Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA. Western blot (1/1,000-1/2,000). Immunohistochemistry on Paraffin Sections (1/50-1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- TARDBP (TAR DNA Binding Protein (TARDBP))
- Alternative Name
- TARDBP (TARDBP Products)
- Background
- TAR DNA binding protein (TARDBP), also known as TDP-43, is a cellular protein. TARDBP was identified as the disease accumulating protein in patients with frontotemporal lobar degeneration (FTLD) with ubiquitin inclusions (FTLD-U) and in amyotrophic lateral sclerosis (ALS). TARDBP functions as a DNA-binding protein and specifically binds to the TAR DNA sequence motifs of HIV. Via this association with TAR motifs, TARDBP acts as a transcriptional repressor and inhibits HIV-1 transcription. In addition, this protein regulates alternate splicing of the cystic fibrosis transmembrane receptor (CFTR) gene.Synonyms: TAR DNA-binding protein 43, TDP-43, TDP43
- Gene ID
- 23435
- UniProt
- Q13148
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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