SIRPG antibody

Catalog No. ABIN316999

Product Details anti-SIRPG Antibody

Target: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRPG antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: This antibody recognises SIRP gamma, a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily.

Characteristics: Synonyms: SIRP-beta-2, SIRP-b2, SIRPB2, SIRP gamma, Signal-regulatory protein gamma,Signal-regulatory protein beta-2, CD172 antigen-like family member B

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Purified recombinant SIRPgamma. CD4.

Clone: OX119

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: 1/50 - 1/200. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Expiry Date: 12 months

Target Details for SIRPG

Target: SIRPG (Signal-Regulatory Protein gamma (SIRPG))

Alternative Name: CD172g / SIRPG (SIRPG Products)

Background: SIRP gamma, also known as CD172g, is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. It is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.Synonyms: CD172 antigen-like family member B, SIRP gamma, SIRP-b2, SIRP-beta-2, SIRPB2, Signal-regulatory protein beta-2, Signal-regulatory protein gamma

Gene ID: 55423

UniProt: Q9P1W8