PD-1 antibody
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- Target See all PD-1 (PDCD1) Antibodies
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This PD-1 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- This antibody recognises CD279, a 55 kDa cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.
- Characteristics
- Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1
- Purification
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Immunogen
- PD-1 transferred BHK cells
- Clone
- RMP1-30
- Isotype
- IgG2b
- Top Product
- Discover our top product PDCD1 Primary Antibody
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anti-Programmed Cell Death 1 (PDCD1) (AA 201-288) antibody
PDCD1 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 41-132) antibodyPDCD1 Reactivity: Human WB, ELISA, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 192-288) antibodyPDCD1 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 3B3D9 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 192-288) antibodyPDCD1 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 8G5B12 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 1D6F6 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reactivity: Human FACS, ELISA, ICC Host: Mouse Monoclonal 3E12A10 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) antibodyPDCD1 Reactivity: Human IHC, ELISA, StM, Coat Host: Mouse Monoclonal PDCD1-2720 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 1-288) antibodyPDCD1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) antibodyPDCD1 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal EH12-2H7 unconjugated
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- Application Notes
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Flow Cytometry: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only. - Expiry Date
- 12 months
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Alternative Name
- CD279 / PD1 (PDCD1 Products)
- Background
- CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1
- Gene ID
- 18566
- UniProt
- Q02242
- Pathways
- Cancer Immune Checkpoints
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