Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD86 antibody (FITC)

CD86 Reactivity: Mouse FACS Host: Rat Monoclonal PO3 FITC
Catalog No. ABIN316884
  • Target See all CD86 Antibodies
    CD86
    Reactivity
    • 138
    • 106
    • 52
    • 19
    • 10
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    Mouse
    Host
    • 78
    • 74
    • 60
    Rat
    Clonality
    • 148
    • 60
    • 2
    Monoclonal
    Conjugate
    • 83
    • 23
    • 19
    • 15
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD86 antibody is conjugated to FITC
    Application
    • 149
    • 90
    • 47
    • 37
    • 33
    • 32
    • 31
    • 24
    • 18
    • 16
    • 14
    • 13
    • 12
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody recognises CD86 (B7-2). The PO3 clone has been reported to block some co-stimulatory functions of CD86.
    Characteristics
    Synonyms: CD28LG2, B70, FUN-1, BU63, T-lymphocyte activation antigen CD86, Activation B7-2antigen, CTLA-4 counter-receptor B7.2
    Purification
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    Immunogen
    Mouse B-cell line, BCL1.
    Clone
    PO3
    Isotype
    IgG2b
    Top Product
    Discover our top product CD86 Primary Antibody
  • Application Notes
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,1 mg/mL
    Buffer
    Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide, 1 % Bovine Serum Albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request). This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by
    Expiry Date
    12 months
  • Target
    CD86
    Alternative Name
    CD86 (CD86 Products)
    Background
    CD86 is an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse, CD86 is expressed at high levels on peripheral blood monocytes, dendritic cells and at low levels on resting B and T-lymphocytes. Expression of CD86 on these cell populations can be increased upon activation. CD86 has been identified, along with CD80 (B7-1) as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses.Synonyms: Activation B7-2 antigen, B7.2, B70, BU63, CD28LG2, CTLA-4 counter-receptor B7.2, FUN-1, T-lymphocyte activation antigen CD86
    Gene ID
    12524
    UniProt
    P42082
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
You are here:
Support