CD79a antibody (AA 202-216) (PE)

Catalog No. ABIN316541

Product Details anti-CD79a Antibody (PE)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Binding Specificity: AA 202-216

Reactivity: Human, Mouse, Rat, Cow, Pig, Monkey, Chicken, Rabbit, Horse, Guinea Pig, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79a antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: This antibody recognises an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45 kDa protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells.

Characteristics: Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1

Clone: HM57

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: use 10 μL of neat antibody to label 1x10^6 cells in 100 μL, Membranepermeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 0.25 mL distilled water

Concentration: 0.1 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3), 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this productcontain a precipitate we recommend microcentrifugation before use.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Alternative Name: CD79a (CD79A Products)

Synonyms: CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody

Background: The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein

Gene ID: 973

UniProt: P11912

Pathways: BCR Signaling