TRIM22 antibody (N-Term)

Catalog No. ABIN311756

Product Details anti-TRIM22 Antibody

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM22 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LANIVERVKE VKMSPQEGQK RDVCEHHGKK LQIFCKEDGK VICWVCELSQ

Cross-Reactivity: Human

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIM22. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM22

Application Details

Application Notes: WB Suggested Anti-TRIM22 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 498 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM22

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Alternative Name: TRIM22 / RNF94 (TRIM22 Products)

Background: TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPSTAF50, RNF94, STAF50
Protein Interaction Partner: EIF4E, UBC, TAB2, CASK, CIC, TRIM22, USP7, RERE, ZZZ3, TAF7, CREB1,
Protein Size: 498

Molecular Weight: 57 kDa

Gene ID: 10346

NCBI Accession: NM_006074, NP_006065

UniProt: Q8IYM9