FUNDC1 antibody (N-Term)

Catalog No. ABIN311553

Product Details anti-FUNDC1 Antibody

Target: FUNDC1 (FUN14 Domain Containing 1 (FUNDC1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUNDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MATRNPPPQD YESDDDSYEV LDLTEYARRH QWWNRVFGHS SGPMVEKYSV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FUNDC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FUNDC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 155 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FUNDC1 antibody (ABIN311553)

Zhang, Yin, Zhang, Qi, Ma, Gao, Wang, Jing: "Spermidine preconditioning ameliorates laurate-induced brain injury by maintaining mitochondrial stability." in: Neurological research, Vol. 39, Issue 3, pp. 248-258, (2017) (PubMed).

Huang, Sivagurunathan, Ting, Jansson, Austin, Kelly, Semsarian, Zhang, Richardson: "Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2? phosphorylation, and the induction of downstream targets." in: The American journal of pathology, Vol. 183, Issue 3, pp. 745-57, (2013) (PubMed).

Target Details for FUNDC1

Target: FUNDC1 (FUN14 Domain Containing 1 (FUNDC1))

Alternative Name: FUNDC1 (FUNDC1 Products)

Background: FUNDC1 belongs to the FUN14 family. The exact function of FUNDC1 remains unknown.
Alias Symbols: MGC51029
Protein Interaction Partner: SLC25A46, MAP1LC3A, MAP1LC3B, SENP2, SH3GLB1, MTERF3, GABARAPL1, GABARAPL2, YES1, TUFM, SNX1, EHHADH, CTBP2, CTBP1, UBC,
Protein Size: 155

Molecular Weight: 17 kDa

Gene ID: 139341

NCBI Accession: NM_173794, NP_776155

UniProt: Q8IVP5