TSPAN32 antibody (Middle Region)

Catalog No. ABIN310831

Product Details anti-TSPAN32 Antibody

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Binding Specificity: Middle Region

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPAN32 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EDCLQGIRSF LRTHQQVASS LTSIGLALTV SALLFSSFLW FAIRCGCSLD

Predicted Reactivity: Horse: 100%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TSPAN32. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSPAN32

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 290 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSPAN32

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Alternative Name: TSPAN32 (TSPAN32 Products)

Background: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as hematopoietic cell function. This gene is described as a member of the tetraspanin superfamily.This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is located among several imprinted genes, however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4 (TSSC4), escapes imprinting. This gene may play a role in malignancies and disease that involve this region as well as hematopoietic cell function. This gene is described as a member of the tetraspanin superfamily. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
Alias Symbols: MGC22455, PHEMX, PHMX, TSSC6, ART1
Protein Size: 290

Molecular Weight: 31 kDa

Gene ID: 10077

NCBI Accession: NM_005705, NP_005696