SLC12A2 antibody (C-Term)

Catalog No. ABIN310505

Product Details anti-SLC12A2 Antibody

Target: SLC12A2 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC12A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IIAFEEIIEP YRLHEDDKEQ DIADKMKEDE PWRITDNELE LYKTKTYRQI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against SLC12A2. It was validated on Western Blot.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC12A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1212 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC12A2 antibody (ABIN310505)

Jansen, Peugh, Roden, Ojemann: "Impaired maturation of cortical GABA(A) receptor expression in pediatric epilepsy." in: Epilepsia, Vol. 51, Issue 8, pp. 1456-67, (2010) (PubMed).

Chen, Sun, Deng, Hao, Chen, Xing, Jia, Ma, Wei, Zhu, Qian, Jiang, He: "Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC." in: Proteomics, Vol. 8, Issue 23-24, pp. 5108-18, (2008) (PubMed).

Target Details for SLC12A2

Target: SLC12A2 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2))

Alternative Name: SLC12A2 (SLC12A2 Products)

Background: By moving chloride into epithelial cells, the Na-K-Cl cotransporter SLC12A2 aids transcellular movement of chloride across both secretory and absorptive epithelia.By moving chloride into epithelial cells, the Na-K-Cl cotransporter SLC12A2 aids transcellular movement of chloride across both secretory and absorptive epithelia (Payne et al., 1995). See also SLC12A1 (MIM 600839) and SLC12A3 (MIM 600968).[supplied by OMIM].
Alias Symbols: BSC, BSC2, MGC104233, NKCC1
Protein Interaction Partner: EGFR, MDM2, ATP4A, COMMD1, UBC, SEC13, STK39, OXSR1, SLC12A2, MAPK14,
Protein Size: 1212

Molecular Weight: 131 kDa

Gene ID: 6558

NCBI Accession: NM_001046, NP_001037

UniProt: P55011

Pathways: Sensory Perception of Sound