IL18RAP antibody (N-Term)

Catalog No. ABIN310291

Product Details anti-IL18RAP Antibody

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18RAP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NRLSPKQVPE HLPFMGSNDL SDVQWYQQPS NGDPLEDIRK SYPHIIQDKC

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IL18RAP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL18RAP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 599 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL18RAP

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Alternative Name: IL18RAP (IL18RAP Products)

Synonyms: IL18RAP antibody, ACPL antibody, CD218b antibody, CDw218b antibody, IL18RB antibody, interleukin 18 receptor accessory protein antibody, IL18RAP antibody, Il18rap antibody

Background: IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
Alias Symbols: ACPL, CDw218b, MGC120589, MGC120590, CD218b, IL18RB
Protein Interaction Partner: APP, IL18, CD48,
Protein Size: 599

Molecular Weight: 66 kDa

Gene ID: 8807

NCBI Accession: NM_003853, NP_003844

UniProt: O95256