PRP6/ANT-1 antibody (C-Term)

Catalog No. ABIN310071

Product Details anti-PRP6/ANT-1 Antibody

Target: PRP6/ANT-1 (PRPF6) (PRP6 Pre-mRNA Processing Factor 6 Homolog (PRPF6))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRP6/ANT-1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FWSQRKITKA REWFHRTVKI DSDLGDAWAF FYKFELQHGT EEQQEEVRKR

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PRPF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PRPF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 941 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRP6/ANT-1

Target: PRP6/ANT-1 (PRPF6) (PRP6 Pre-mRNA Processing Factor 6 Homolog (PRPF6))

Alternative Name: PRPF6 (PRPF6 Products)

Background: PRPF6 appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. PRPF6 also can bind androgen receptor, providing a link between transcriptional activation and splicing.The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.
Alias Symbols: ANT-1, TOM, ANT1, Prp6, hPrp6, U5-102K, C20orf14
Protein Interaction Partner: SUMO2, SUMO3, UBC, MDM2, PASK, RPA3, RPA2, RPA1, EED, rev, PARK2, PRPF4B, UBD, HDAC11, CTNNB1, MMS19, MYC, IK, PRPF31, SRRM2, CD2BP2, WHSC1, NOTCH1, ZNF326, TRA2A, PRPF19, SF3B3, NCSTN, SNRNP200, ACIN1, U2AF2, SUPT16H, PRPF8, RBM14, SAP18, THRAP3, EIF4A3,
Protein Size: 941

Molecular Weight: 104 kDa

Gene ID: 24148

NCBI Accession: NM_012469, NP_036601

UniProt: O94906

Pathways: Ribonucleoprotein Complex Subunit Organization, Proton Transport, Dicarboxylic Acid Transport