CXXC1 antibody (C-Term)

Catalog No. ABIN309931

Product Details anti-CXXC1 Antibody

Target: CXXC1 (CXXC Finger Protein 1 (CXXC1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RVWYKLDELF EQERNVRTAM TNRAGLLALM LHQTIQHDPL TTDLRSSADR

Predicted Reactivity: Cow: 86%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CXXC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CXXC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 656 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CXXC1

Target: CXXC1 (CXXC Finger Protein 1 (CXXC1))

Alternative Name: CXXC1 (CXXC1 Products)

Background: Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression.Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001).[supplied by OMIM].
Alias Symbols: 2410002I16Rik, 5830420C16Rik, CGBP, HsT2645, PCCX1, PHF18, hCGBP, CFP1, SPP1, ZCGPC1
Protein Interaction Partner: RBBP5, MEOX2, WDR5, SETD1A, ASH2L, TAX1BP1, WDR82, UBC, RNF2, HSP90AA1, SETD1B, TBP, MYC, SUMO2, PPP1CA, tat, NR5A1, SMURF1, HIST2H3C, HIST2H4A, MEN1, KIFC1, DNMT1, WDR82P1, WDR77, KMT2D, KMT2A,
Protein Size: 656

Molecular Weight: 76 kDa

Gene ID: 30827

NCBI Accession: NM_014593, NP_055408

UniProt: Q9P0U4

Pathways: ER-Nucleus Signaling