CREG1 antibody (N-Term)

Catalog No. ABIN309887

Product Details anti-CREG1 Antibody

Target: CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREG1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAGLSRGSAR ALLAALLAST LLALLVSPAR GRGGRDHGDW DEASRLPPLP

Predicted Reactivity: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CREG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CREG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 220 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CREG1

Target: CREG1 (Cellular Repressor of E1A-Stimulated Genes 1 (CREG1))

Alternative Name: CREG1 (CREG1 Products)

Synonyms: CREG1 antibody, CREG antibody, AA755314 antibody, Creg antibody, cellular repressor of E1A stimulated genes 1 antibody, cellular repressor of E1A-stimulated genes 1 antibody, CREG1 antibody, creg1 antibody, Creg1 antibody

Background: The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG1 antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro.The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
Alias Symbols: CREG
Protein Interaction Partner: FBXO6, CAPN1, TBP, RBL2, RB1, IGF2R, RBL1,
Protein Size: 220

Molecular Weight: 24 kDa

Gene ID: 8804

NCBI Accession: NM_003851, NP_003842

UniProt: O75629