TRIM21 antibody (N-Term)
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- Target See all TRIM21 Antibodies
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Pig, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRIM21 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CPVCRQRFLL KNLRPNRQLA NMVNNLKEIS QEAREGTQGE RCAVHGERLH
- Predicted Reactivity
- Cow: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against TRIM21. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM21
- Top Product
- Discover our top product TRIM21 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 475 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
- Alternative Name
- TRIM21 (TRIM21 Products)
- Background
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TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RNF81, RO52, SSA, SSA1
Protein Interaction Partner: TRIM39, IGHV4-31, TXN2, GRAP, UBE2I, TRIM21, IGHG1, USP15, HAUS2, UBE2D2, UBC, FBXO6, UBD, NPM1, PAN2, ROR1, NOS2, MYC, IQCB1, USP2, VCP, USP4, CDC34, CBL, UBC4, UBE2C, UBE2L3, UBE2H, UBE2D1, TROVE2, TRIM27, MNAT1, FCGR2A, CD52, DCP2, ZFPM1, TRIM5, TRIM8,
Protein Size: 475 - Molecular Weight
- 54 kDa
- Gene ID
- 6737
- NCBI Accession
- NM_003141, NP_003132
- UniProt
- P19474
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