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CD81 antibody (Biotin)

CD81 Reactivity: Mouse FACS Host: Mouse Monoclonal Eat2 Biotin

Catalog No. ABIN307696

Datasheet as PDF

Target See all CD81 Antibodies

CD81
Reactivity
131

90

37

17

17

9

9

5

3

1

1

1

1

1
Mouse
Host
72

65

29

4

3

1
Mouse
Compatible Secondaries
Clonality
120

48

3
Monoclonal
Conjugate
79

21

16

13

6

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD81 antibody is conjugated to Biotin
Application
121

87

44

41

31

31

30

29

17

14

13

13

5

4

3

3

1

1

1

1

1

1
Flow Cytometry (FACS)

Specificity

Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and non-killer cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells.

Purification

Purified

Immunogen

Type of Immunogen: Native protein

Clone

Eat2

Isotype

IgG1

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anti-CD81 (CD81) antibody
KO Validated CD81 Reactivity: Human FACS, WB, IF, IHC (p), ICC, BP Host: Rabbit Polyclonal unconjugated

anti-CD81 (CD81) (AA 1-100) antibody
CD81 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-CD81 (CD81) antibody
CD81 Reactivity: Human, Rabbit, Cat FACS, WB, IP, IHC (p), ICC Host: Mouse Monoclonal M38 unconjugated

anti-CD81 (CD81) antibody
CD81 Reactivity: Human FACS, WB, IHC, ELISA Host: Rabbit Monoclonal 9F7 unconjugated Recombinant Antibody

anti-CD81 (CD81) antibody (FITC)
CD81 Reactivity: Human, Rabbit, Cat FACS Host: Mouse Monoclonal M38 FITC

anti-CD81 (CD81) (AA 176-203), (C-Term) antibody
CD81 Reactivity: Human, Mouse FACS, WB, IHC (p) Host: Rabbit Polyclonal RB19768 unconjugated

anti-CD81 (CD81) antibody (PE)
CD81 Reactivity: Human, Rabbit, Cat FACS Host: Mouse Monoclonal M38 PE

anti-CD81 (CD81) antibody
CD81 Reactivity: Human, Mouse, Rat FACS, WB, IHC, IF, Func, StM Host: Mouse Monoclonal 1-3-3-22 unconjugated

anti-CD81 (CD81) antibody
CD81 Reactivity: Human, Mouse, Rat ELISA, Coat Host: Rabbit Monoclonal C81-2885R unconjugated Recombinant Antibody

anti-CD81 (CD81) antibody
CD81 Reactivity: Human FACS, cELISA Host: Rat Monoclonal QV-6A8-S3 unconjugated

Application Notes

Approved: Flo (1 μg/10 x10⁶)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment

Target Species of Antibody: Mouse

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

PBS, 0.02 % sodium azide, EIA grade BSA.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

CD81

Alternative Name

CD81 (CD81 Products)

Background

Name/Gene ID: CD81
Family: Tetraspan

Synonyms: CD81, CD81 antigen, CD81 Molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28

Gene ID

975

UniProt

P60033

Pathways

Inositol Metabolic Process, Hepatitis C