Adiponectin Receptor 2 antibody (C-Term)

Catalog No. ABIN306947

Product Details anti-Adiponectin Receptor 2 Antibody

Target: Adiponectin Receptor 2 (ADIPOR2)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adiponectin Receptor 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Characteristics: Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2, PAQR2,ADR2 functions as a receptor for globular and full-length adiponectin (APM1), which is an essential hormone secreted by adipocytes that acts as an antidiabetic. ADR2 is also probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. ADR2 mediates an increase in AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin and has some intermediate-affinity receptor activity for both globular and full-length adiponectin. ADR2 may form homo and heteromultimers.

Purification: Ammonium sulfate precipitation

Immunogen: Rabbits were immunized with a synthetic peptide near the C terminus of human adiponectin receptor 2 proteins

Application Details

Application Notes: Antibody can be used for Western blotting (5-10 μg/mL) and ELISA. Other applications not yet tested. Cross reacts with Human ADR1. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for Adiponectin Receptor 2

Target: Adiponectin Receptor 2 (ADIPOR2)

Alternative Name: Adiponectin Receptor 2 (ADIPOR2 Products)

UniProt: Q86V24

Pathways: AMPK Signaling