Western blot. Immunohistochemistry on paraffin sections: 5 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Zempel, Thies, Mandelkow, Mandelkow: "Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 36, pp. 11938-50, (2010) (PubMed).
BRSK1 is thought to be involved in the regulation of G2/M arrest and to function as a checkpoint kinase following DNA damage induced by UV or methyl methane sulfonate. BRSK1 phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.Synonyms: BR serine/threonine-protein kinase 1, KIAA1811, SAD-B, SAD1, SAD1 kinase, Serine/threonine kinase SAD-B