ICAM1 antibody (Biotin)
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- Target See all ICAM1 Antibodies
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ICAM1 antibody is conjugated to Biotin
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Application
- Flow Cytometry (FACS)
- Characteristics
- Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
- Immunogen
- Raji cells and spleen cells fused with NS1 cells
- Clone
- 1H4
- Isotype
- IgG2b
- Top Product
- Discover our top product ICAM1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Alternative Name
- CD54 / ICAM1 (ICAM1 Products)
- Target Type
- Viral Protein
- Background
- CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
- UniProt
- P05362
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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