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Cadherin 5 antibody (AA 1-258)

CDH5 Reactivity: Cow WB, ELISA, FACS, IHC (fro) Host: Rabbit Polyclonal unconjugated

Catalog No. ABIN285709

Datasheet as PDF

Target See all Cadherin 5 (CDH5) Antibodies

Cadherin 5 (CDH5)
Binding Specificity
16

13

6

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-258
Reactivity
93

58

43

4

2

1

1

1

1

1
Cow
Host
80

25

7

1
Rabbit
Compatible Secondaries
Clonality
78

35
Polyclonal
Conjugate
72

7

6

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Cadherin 5 antibody is un-conjugated
Application
86

40

38

37

19

15

14

14

13

10

10

7

5

4

3

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Cow (Bovine), Mouse (Murine), Rat (Rattus)

Purification

Purified

Immunogen

CD144 antibody was raised in rabbit using recombinant protein fragments corresponding to amino acids 1-258 of VE-cadherin as the immunogen.

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CDH5 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

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CDH5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal conditions should be determined byt he investigator.

Restrictions

For Research Use only
Concentration

Lot specific

Buffer

Purified IgG supplied in PBS.

Handling Advice

Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage

-20 °C

Storage Comment

Aliquot and store at -20 °C.
Target

Cadherin 5 (CDH5)

Alternative Name

CD144 (CDH5 Products)

Background

VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cellcontacts, called adherens junctions.

Pathways

Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2