CD59 antibody
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- Target See all CD59 Antibodies
- CD59
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD59 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Cross-Reactivity
- Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- P282 (H19)
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD59 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD59
- Alternative Name
- CD59 (CD59 Products)
- Background
- CD59 is a 19-25 kD glycosylphosphatidylinositol (GPI)-anchored glycoprotein also known as protectin, MACIF, and H19. It is broadly expressed on hematopoietic and non-hematopoietic cells. CD59 inhibits the cytolytic activity of complement by binding to C9, inhibiting incorporation into C5b-8, and preventing the terminal steps in complement polymerization of the membrane attack complex. CD59 has also been reported to play a role in T cell activation.
- Pathways
- Complement System
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