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TEK antibody

TEK Reactivity: Human FACS Host: Mouse Monoclonal 33-1 (Ab33) unconjugated
Catalog No. ABIN2664377
  • Target See all TEK Antibodies
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Reactivity
    • 124
    • 61
    • 46
    • 21
    • 3
    • 3
    Human
    Host
    • 116
    • 18
    • 4
    • 3
    • 2
    Mouse
    Clonality
    • 122
    • 21
    Monoclonal
    Conjugate
    • 72
    • 10
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TEK antibody is un-conjugated
    Application
    • 76
    • 57
    • 40
    • 40
    • 30
    • 30
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    33-1 (Ab33)
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TEK Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Alternative Name
    CD202b (TEK Products)
    Background
    CD202b is a 145 kD type I transmembrane protein, also known as Tie2 or TEK. It is a member of the receptor tyrosine kinase (RTK) family of proteins and is expressed by endothelial cells and their progenitors, quiescent hematopoietic stem cells (HSCs), and a subpopulation of monocytes. Angiopoietin-1 (Ang-1) is an activator of CD202b to promote, maintain, and stabilize mature vessels and to maintain HSCs in quiescent state. Ang-2 is another ligand of CD202b, which is involved in postnatal angiogenesis and in antagonizing the effects of Ang-1. Tie2 binds to Ang-4 as well.
    Pathways
    RTK Signaling, Growth Factor Binding
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