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CSF1R antibody (PE)

CSF1R Reactivity: Mouse IHC, FACS, IF Host: Rat Monoclonal AFS98 PE
Catalog No. ABIN2662953
  • Target See all CSF1R Antibodies
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Reactivity
    • 183
    • 107
    • 74
    • 17
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 199
    • 19
    • 15
    • 3
    • 2
    • 1
    Rat
    Clonality
    • 200
    • 38
    • 1
    Monoclonal
    Conjugate
    • 97
    • 23
    • 13
    • 11
    • 10
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    This CSF1R antibody is conjugated to PE
    Application
    • 148
    • 93
    • 87
    • 58
    • 39
    • 26
    • 22
    • 21
    • 11
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    AFS98
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CSF1R Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Alternative Name
    CD115 (CSF1R Products)
    Background
    CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
    Pathways
    RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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