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ICAM1 antibody (PE)

ICAM1 Reactivity: Rat FACS Host: Mouse Monoclonal 1A29 PE
Catalog No. ABIN2662658
  • Target See all ICAM1 Antibodies
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Reactivity
    • 218
    • 73
    • 38
    • 10
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Rat
    Host
    • 124
    • 114
    • 22
    • 3
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 138
    • 125
    • 1
    Monoclonal
    Conjugate
    • 121
    • 25
    • 21
    • 18
    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM1 antibody is conjugated to PE
    Application
    • 167
    • 146
    • 65
    • 58
    • 45
    • 40
    • 34
    • 31
    • 28
    • 25
    • 24
    • 19
    • 12
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    1A29
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Alternative Name
    CD54 (ICAM1 Products)
    Target Type
    Viral Protein
    Background
    CD54 is an 85 kD protein also known as ICAM-1. It is a member of the immunoglobulin superfamily that is expressed on high endothelial venules in lymphoid tissue, peripheral blood monocytes, dendritic cells, granulocytes and thymic stromal cells. CD54 is weakly expressed on T and B cells, although expression can be increased by activation (especially on endothelial cells). ICAM-1 is an important protein in cell adhesion, inflammation and immune responses. CD54 has been shown to bind to CD11a/CD18 (LFA-1), CD11b/CD18, CD11c/CD18, CD43, fibrinogen, and hyaluronan. The 1A29 antibody has been reported to block T cell aggregation and binding of lymphocytes to HEV-derived endothelial cells and purified ICAM-1 protein.
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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