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Cytochrome C antibody (Biotin)

CYCS Reactivity: Human, Rat, Mouse FACS Host: Mouse Monoclonal 6H2-B4 Biotin
Catalog No. ABIN2661159
  • Target See all Cytochrome C (CYCS) Antibodies
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    Reactivity
    • 143
    • 111
    • 91
    • 41
    • 30
    • 23
    • 22
    • 19
    • 18
    • 16
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 90
    • 67
    • 6
    • 1
    Mouse
    Clonality
    • 84
    • 79
    • 1
    Monoclonal
    Conjugate
    • 96
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cytochrome C antibody is conjugated to Biotin
    Application
    • 127
    • 48
    • 39
    • 37
    • 35
    • 28
    • 27
    • 20
    • 14
    • 13
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Clone
    6H2-B4
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CYCS Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
    Alternative Name
    Cytochrome C (CYCS Products)
    Background
    Cytochrome c is a 15 kD protein found in the mitochondrial intermembrane space with a heme-binding domain. Cytochrome c is a component of the electron transport chain, the heme group transfers electrons from cytochrome b-c1 complex to cytochrome oxidase complex. Cytochrome c initiates apoptosis by release to cytoplasm and binding Apaf-1 which activates procaspase 9. Cytochrome c interacts with the cytochrome b-c1 complex, cytochrome oxidase complex, heme, Apaf-1, and Caspase 9 proteins. The 6H2.B4 monoclonal antibody recognizes human, mouse, and rat cytochrome-c and has been shown to be useful for intracellular flow cytometric staining, Western blotting, immunoprecipitation, and immunofluorescence staining.
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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