Cytochrome C antibody (Biotin)
-
- Target See all Cytochrome C (CYCS) Antibodies
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
-
Reactivity
- Human, Rat, Mouse
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This Cytochrome C antibody is conjugated to Biotin
-
Application
- Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- Clone
- 6H2-B4
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CYCS Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- Target
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
- Alternative Name
- Cytochrome C (CYCS Products)
- Background
- Cytochrome c is a 15 kD protein found in the mitochondrial intermembrane space with a heme-binding domain. Cytochrome c is a component of the electron transport chain, the heme group transfers electrons from cytochrome b-c1 complex to cytochrome oxidase complex. Cytochrome c initiates apoptosis by release to cytoplasm and binding Apaf-1 which activates procaspase 9. Cytochrome c interacts with the cytochrome b-c1 complex, cytochrome oxidase complex, heme, Apaf-1, and Caspase 9 proteins. The 6H2.B4 monoclonal antibody recognizes human, mouse, and rat cytochrome-c and has been shown to be useful for intracellular flow cytometric staining, Western blotting, immunoprecipitation, and immunofluorescence staining.
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
-