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NGFR antibody (PerCP-Cy5.5)

NGFR Reactivity: Human FACS Host: Mouse Monoclonal ME20-4 PerCP-Cy5.5
Catalog No. ABIN2660066
  • Target See all NGFR Antibodies
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Reactivity
    • 156
    • 65
    • 57
    • 28
    • 26
    • 26
    • 25
    • 21
    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 87
    • 76
    • 4
    • 1
    Mouse
    Clonality
    • 94
    • 74
    Monoclonal
    Conjugate
    • 86
    • 14
    • 11
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NGFR antibody is conjugated to PerCP-Cy5.5
    Application
    • 92
    • 83
    • 56
    • 47
    • 41
    • 28
    • 27
    • 19
    • 16
    • 15
    • 15
    • 12
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Cross-Reactivity
    Monkey, Raccoon (Procyon lotor), Sheep (Ovine), Cat (Feline), Dog (Canine), Pig (Porcine), Rabbit
    Purification
    The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
    Clone
    ME20-4
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product NGFR Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Alternative Name
    CD271 (NGFR Products)
    Background
    CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.
    Pathways
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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