-
- Target See all CD16 Antibodies
- CD16
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This CD16 antibody is conjugated to PE-Cy5
-
Application
- Flow Cytometry (FACS)
- Cross-Reactivity
- Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Marmoset, Capuchin Monkey, Pigtailed Macaque, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.), Saguinus oedipus
- Purification
- The antibody was purified by affinity chromatography, and conjugated with PE/Cy5 under optimal conditions. The solution is free of unconjugated PE/Cy5 and unconjugated antibody.
- Clone
- 3G8
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD16 Primary Antibody
-
anti-CD16 (CD16) antibody
CD16 Reactivity: Human, Non-Human Primate FACS, IP, IHC (fro) Host: Mouse Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibodyCD16 Reactivity: Human, Non-Human Primate FACS, IP Host: Mouse Monoclonal LNK16 unconjugated
anti-CD16 (CD16) antibody (FITC)CD16 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal LNK16 FITC
anti-CD16 (CD16) antibodyCD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibodyCD16 Reactivity: Human, Pig, Non-Human Primate FACS Host: Mouse Monoclonal MEM-168 unconjugated
anti-CD16 (CD16) antibodyCD16 Reactivity: Human FACS, IP, Func, WB Host: Mouse Monoclonal MEM-154 unconjugated
anti-CD16 (CD16) antibody (Biotin)CD16 Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-154 Biotin
anti-CD16 (CD16) (AA 17-208) antibodyCD16 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 2G10A9 unconjugated
anti-CD16 (CD16) antibodyCD16 Reactivity: Human, Non-Human Primate FACS, IP, Func, IHC (fro) Host: Mouse Monoclonal 3G8 unconjugated
anti-CD16 (CD16) antibodyCD16 Reactivity: Human FACS Host: Mouse Monoclonal GRM1 unconjugated
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- Target
- CD16
- Alternative Name
- CD16 (CD16 Products)
- Background
- CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95 % homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-
You are here:
