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CD8 alpha antibody (APC)

Name: CD8 alpha antibody (APC)
SKU: ABIN2658876
Availability: OutOfStock

CD8A Reactivity: Mouse FACS, IHC, IP, IF, BR Host: Rat Monoclonal 53-6-7 APC

FACS

1 image

Catalog No. ABIN2658876

Datasheet as PDF

Target See all CD8 alpha (CD8A) Antibodies

CD8 alpha (CD8A) (CD8a Molecule (CD8A))
Reactivity
180

112

46

45

13

7

4

2

2

1

1

1

1

1

1

1

1
Mouse
Host
151

124

96
Rat
Compatible Secondaries
Clonality
269

97

2
Monoclonal
Conjugate
131

41

29

25

24

8

8

8

7

6

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD8 alpha antibody is conjugated to APC
Application
296

114

84

62

61

48

32

20

15

14

13

11

7

6

6

6

5

4

3

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Blocking Reagent (BR)

Purification

The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone

53-6-7

Isotype

IgG2a kappa

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CD8A Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 8H8A8 unconjugated

anti-CD8a Molecule (CD8A) antibody
CD8A Reactivity: Mouse FACS, IP, IHC (fro), IHC (p), ICC, Func Host: Rat Monoclonal 53-6-7 unconjugated

anti-CD8a Molecule (CD8A) antibody
CD8A Reactivity: Mouse FACS, IP, IHC (fro), IHC (p), ICC Host: Rat Monoclonal 53-6-7 unconjugated

anti-CD8a Molecule (CD8A) antibody (FITC)
CD8A Reactivity: Mouse FACS Host: Rat Monoclonal 53-6-7 FITC

anti-CD8a Molecule (CD8A) antibody (PE)
CD8A Reactivity: Mouse FACS Host: Rat Monoclonal 53-6-7 PE

anti-CD8a Molecule (CD8A) (AA 51-150) antibody
CD8A Reactivity: Human, Rat, Chicken FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated

anti-CD8a Molecule (CD8A) antibody
CD8A Reactivity: Human IHC, WB, IP, ELISA Host: Rabbit Monoclonal 2F2 unconjugated Recombinant Antibody

anti-CD8a Molecule (CD8A) (AA 22-182) antibody
CD8A Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 6A9A5 unconjugated

anti-CD8a Molecule (CD8A) antibody
CD8A Reactivity: Human IHC, StM, ISt Host: Mouse Monoclonal C8-468 unconjugated

anti-CD8a Molecule (CD8A) (AA 28-196) antibody
CD8A Reactivity: Mouse, Rat FACS, IHC, WB, ELISA, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

0.2 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Protect from prolonged exposure to light. Do not freeze.

Storage

4 °C

Storage Comment

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Alternative Name

CD8a (CD8A Products)

Background

CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

Pathways

TCR Signaling