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FAS antibody (APC)
FAS
Reactivity: Human
FACS, ICFC
Host: Mouse
Monoclonal
DX2
APC
Product Details anti-FAS Antibody (APC)
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Target
See all FAS Antibodies
FAS
(TNF Receptor Superfamily, Member 6 (FAS))
Reactivity
All reactivities for FAS antibodies
Human
Host
All hosts for FAS antibodies
Mouse
Clonality
All clonalities for FAS antibodies
Monoclonal
Conjugate
All conjugates for FAS antibodies
This FAS antibody is conjugated to APC
Application
All applications for FAS antibodies
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
Cross-Reactivity
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Baboon, Capuchin Monkey, Chimpanzee, Marmoset, Saguinus oedipus, Cynomolgus, Pigtailed Macaque, Rhesus Monkey, Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
Purification
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Clone
DX2
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for FAS
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Target
FAS
(TNF Receptor Superfamily, Member 6 (FAS))
Alternative Name
CD95 (FAS Products )
Background
CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
Pathways
p53 Signaling , Apoptosis , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity
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