CD4 antibody (Alexa Fluor 700)
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- Target See all CD4 Antibodies
- CD4
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD4 antibody is conjugated to Alexa Fluor 700
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Application
- Flow Cytometry (FACS)
- Cross-Reactivity
- Chimpanzee, Cynomolgus, Rhesus Monkey
- Purification
- The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 700 under optimal conditions.
- Clone
- OKT4
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product CD4 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Target
- CD4
- Alternative Name
- CD4 (CD4 Products)
- Background
- CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.
- Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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