UGT8 antibody

Catalog No. ABIN265113

Product Details anti-UGT8 Antibody

Target: UGT8 (UDP Glycosyltransferase 8 (UGT8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Ceramide Glycosyltransferase. Other species not tested.

Purification: Purified

Immunogen: Synthetic peptide derived from human ceramide glycosyltransferase protein

Application Details

Application Notes: ELISA. Western Blot: 5 - 10 μg/mL. Positive Control: Found in all tissues examined.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.08 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for UGT8

Target: UGT8 (UDP Glycosyltransferase 8 (UGT8))

Alternative Name: UGT8 / UGT4 (UGT8 Products)

Background: May serve as a flippase as well as a glucosyltransferase that transfers glucose to ceramide. It Catalzes, UDP-glucose + Nacylsphingosine = UDP + D-glucosyl-N-acylsphingosine. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis, first glycosylation step. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates.Synonyms: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT, Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase

Gene ID: 7368

NCBI Accession: NP_001121646

UniProt: Q16880

Pathways: Cell-Cell Junction Organization