PPIB antibody (AA 26-216)

Catalog No. ABIN263993

Product Details anti-PPIB Antibody

Target: PPIB (Cyclophilin B (PPIB))

Binding Specificity: AA 26-216

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPIB antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Cyclophilin B.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: PPIase B, Rotamase B, S-cyclophilin, CYP-S1, PPIB, CYPB, SCYLP, Peptidyl-prolyl cis-transisomerase B

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human Cyclophilin B (26-216aa) purified from E. coli

Clone: K2E2

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot: 1: 1,000 approx. 1: 2,000 (starting dilution 1: 1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PPIB

Target: PPIB (Cyclophilin B (PPIB))

Alternative Name: Cyclophilin B (PPIB Products)

Background: Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Cyclophilin B is necessary for the prolactin-induced proliferation, cell growth, and the nuclear retrotransport of prolactin.Synonyms: CYP-S1, CYPB, PPIB, PPIase B, Peptidyl-prolyl cis-trans isomerase B, Rotamase B, S-cyclophilin, SCYLP

Gene ID: 5479

UniProt: P23284