VCAM1 antibody
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- Target See all VCAM1 Antibodies
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This VCAM1 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- Human CD106
- Purification
- Purified
- Immunogen
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B-K9 is a mouse monoclonal IgG1 antibody derived by fusion of X63/Ag8.653 mouse myeloma cells with spleen cells from BALB/c mice immunized with activated human umbilical vein endothelial cells.
Type of Immunogen: Cells - Clone
- B-K9
- Isotype
- IgG1
- Top Product
- Discover our top product VCAM1 Primary Antibody
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- Application Notes
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Approved: Flo
Usage: CD106 is a 110kD type 1 transmembrane sialoglycoprotein, which is also known as vascular cell adhesion molecule 1 (VCAM-1). The CD106 protein is primarily expressed on activated vascular endothelium but has also been detected on dendritic cell types, macrophages and non-vascular cells in certain tissues. Expression of CD106 is induced by inflammatory stimuli and cytokines. CD106 binds to the integrins CD49d/CD29 (also known as VLA4) and alpha4beta7 and is important in leucocyte-endothelial cell adhesion and signal transduction. The CD106 protein is thought to play a key role in the migration of leucocyte from the blood into tissues, particularly at sites of inflammation. Studies suggest that CD106 may also play a role in the development of rheumatoid arthritis and atherosclerosis. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C, or in small aliquots at -20°C.
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- Target
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
- Alternative Name
- VCAM1 / CD106 (VCAM1 Products)
- Background
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Name/Gene ID: VCAM1
Family: ICAM
Synonyms: VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1 - Gene ID
- 7412
- Pathways
- Carbohydrate Homeostasis
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