ITGAL antibody

Catalog No. ABIN2624324

Product Details anti-ITGAL Antibody

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: Human CD11a. Reported to inhibit the cytolytic activity of various human cytotoxic T-cell clones including HG-38 and HG-31.

Purification: Purified

Immunogen: NKI (SPV)-L1 is a mouse monoclonal IgG1 antibody derived by fusion of Sp2/0 mouse myeloma cells with splenocytes from a BALB/c mouse immunized with cytotoxic T-cell clone HG-38.

Type of Immunogen: Cells

Clone: NKI (SPV)-L1

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, ICC, IP

Usage: Integrin alpha L (antigen CD11A, p180, lymphocyte function-associated antigen 1. alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and co-stimulatory signaling. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C, or in small aliquots at -20°C.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: ITGAL / CD11a (ITGAL Products)

Background: Name/Gene ID: ITGAL
Family: Integrin

Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A

Gene ID: 3683

Pathways: Activated T Cell Proliferation, Integrin Complex