CD22 antibody

Catalog No. ABIN2618441

Product Details anti-CD22 Antibody

Target: CD22 (CD22 Molecule (CD22))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD22 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificity: HLA class I heavy chains (CD22).

Purification: Purified

Immunogen: 3H4 is a mouse monoclonal IgG1 antibody derived by fusion of SP2/0-Ag14 mouse myeloma cells with spleen cells from BALB/c mice immunized with Daudi cells, a Burkitt's lymphoma cell line.

Type of Immunogen: Cells

Clone: 3H4

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, ICC

Usage: CD22 is a 140kD transmembrane type 1 protein, which is a member of the sialic acid binding immunoglobulin (Ig)-like lectin family of proteins. CD22 is a B-lymphocyte specific protein, which is differentially expressed during B-cell development. It is expressed in the cytoplasm of immature B-cells and on the surface of mature B-cells. The CD22 Molecule functions as an adhesion receptor, binding to alpha 2-6 linked sialic acids on glycoproteins expressed by leucocytes and erythrocytes. The molecule is also involved in the regulation of B-cell antigen receptor signaling.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C, or in small aliquots at -20°C.

Target Details for CD22

Target: CD22 (CD22 Molecule (CD22))

Alternative Name: CD22 (CD22 Products)

Background: Name/Gene ID: CD22
Family: Immunoglobulin

Synonyms: CD22, CD22 Molecule, CD22 antigen, SIGLEC2, SIGLEC-2, T-cell surface antigen Leu-14, B-cell receptor CD22, BL-CAM

Gene ID: 933