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CD80 antibody (FITC)

CD80 Reactivity: Mouse FACS Host: Hamster Monoclonal 16-10A1 FITC

Catalog No. ABIN2567927

Datasheet as PDF

Target See all CD80 Antibodies

CD80
Reactivity
140

100

45

6

6

5

1

1

1
Mouse
Host
91

72

20

20

10

2

1
Hamster
Clonality
134

79

2
Monoclonal
Conjugate
90

19

17

16

11

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This CD80 antibody is conjugated to FITC
Application
126

90

66

35

33

22

14

13

13

12

11

10

8

5

4

2

2

2

1

1

1

1

1
Flow Cytometry (FACS)

Specificity

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR).

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone

16-10A1

Isotype

IgG

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anti-CD80 (CD80) antibody
CD80 Reactivity: Mouse, Dog FACS, IP, IHC (fro) Host: Armenian Hamster Monoclonal 16-10A1 unconjugated

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CD80 Reactivity: Mouse WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody
CD80 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-233 unconjugated

anti-CD80 (CD80) (AA 251-321) antibody
CD80 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)
CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 FITC

anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)
CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PerCP

anti-CD80 (CD80) (Extracellular Domain) antibody (APC)
CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 APC

anti-CD80 (CD80) (Extracellular Domain) antibody (PE)
CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PE

anti-CD80 (CD80) antibody
CD80 Reactivity: Human ELISA, IHC, ICC Host: Mouse Monoclonal 2A2 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.5 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD80

Alternative Name

CD80 (CD80 Products)

Background

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Gene ID

12519

UniProt

Q00609

Pathways

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints