CD4 antibody (PE)
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- Target See all CD4 Antibodies
- CD4
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD4 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Clone
- RM4-5
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD4 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- Target
- CD4
- Alternative Name
- CD4 (CD4 Products)
- Background
- The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
- Gene ID
- 12504
- UniProt
- P06332
- Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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