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CD3 antibody

CD3 Reactivity: Human FACS, IHC, Func Host: Mouse Monoclonal OKT3 unconjugated

Catalog No. ABIN2567500

Datasheet as PDF

Target See all CD3 Antibodies

CD3
Reactivity
183

104

26

20

17

10

8

8

7

7

5

3

2

1
Human
Host
218

53

20

13

9

2
Mouse
Compatible Secondaries
Clonality
303

6

1
Monoclonal
Conjugate
96

39

32

23

23

11

9

8

6

5

5

5

4

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD3 antibody is un-conjugated
Application
288

82

58

52

46

37

33

23

9

8

7

6

4

3

2

2

2

2

2

2

2

2

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Specificity

The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex.

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Clone

OKT3

Isotype

IgG2a kappa

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CD3 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-57 Biotin

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CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PerCP

anti-CD3 (CD3) antibody (PerCP)
CD3 Reactivity: Human FACS Host: Mouse Monoclonal MEM-57 PerCP

anti-CD3 (CD3) antibody (APC)
CD3 Reactivity: Human FACS Host: Mouse Monoclonal MEM-57 APC

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C. Do not freeze.
Target

CD3

Alternative Name

CD3 (CD3 Products)

Background

The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.

Gene ID

916

UniProt

P07766

Pathways

TCR Signaling, Ubiquitin Proteasome Pathway