CD3 antibody (FITC)

Catalog No. ABIN2567493

Product Details anti-CD3 Antibody (FITC)

Target: CD3

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR).

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone: G4-18

Isotype: IgG3 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Target Details for CD3

Target: CD3

Alternative Name: CD3 (CD3 Products)

Background: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.

Gene ID: 25710

UniProt: P19377

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway