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CD3 antibody

CD3 Reactivity: Rat FACS, IHC, Func Host: Mouse Monoclonal G4-18 unconjugated

Catalog No. ABIN2567492

Datasheet as PDF

Target See all CD3 Antibodies

CD3
Reactivity
183

104

25

20

17

10

8

8

7

7

5

3

2

1
Rat
Host
217

53

20

13

9

2
Mouse
Compatible Secondaries
Clonality
302

6

1
Monoclonal
Conjugate
95

39

32

23

23

11

9

8

6

5

5

5

4

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD3 antibody is un-conjugated
Application
287

82

58

51

45

37

33

23

9

8

7

6

4

3

2

2

2

2

2

2

2

2

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)

Specificity

The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR).

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Clone

G4-18

Isotype

IgG3 kappa

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anti-CD3 (CD3) antibody (APC)
CD3 Reactivity: Human FACS Host: Mouse Monoclonal MEM-57 APC

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C. Do not freeze.
Target

CD3

Alternative Name

CD3 (CD3 Products)

Background

The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.

Gene ID

25710

UniProt

P19377

Pathways

TCR Signaling, Ubiquitin Proteasome Pathway