CD16 antibody

Catalog No. ABIN2567259

The Mouse Monoclonal anti-CD16 antibody has been validated for FACS and Func. It is suitable to detect CD16 in samples from Human.

Quick Overview for CD16 antibody (ABIN2567259)

Target: CD16

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: CB16

Product Details anti-CD16 Antibody

Specificity: The CB15 monoclonal antibody specifically binds to human CD16, a low affinity Fc receptor.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Storage: 4 °C

Storage Comment: The product should be stored undiluted at 4°C. Do not freeze.

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background: The CB15 monoclonal antibody specifically binds to human CD16, a low affinity Fc receptor. It is expressed on NK, neutrophils, macrophages, monocytes, and placental trophoblasts. CD16 is expressed in CD16a and CD16b forms. CD16a is a polyeptide anchored transmembrane protein and CD16b is a monomeric glycosylphosphatidylinositol (GPI)-anchored protein found in neutrophils. CD16 is reported to be involved in NK cell activation and signal transduction.

Gene ID: 2214

UniProt: P08637

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process