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ITGAL antibody

ITGAL Reactivity: Mouse FACS, Func Host: Rat Monoclonal M17-4 unconjugated
Catalog No. ABIN2567122
  • Target See all ITGAL Antibodies
    ITGAL (Integrin alpha-L (ITGAL))
    Reactivity
    • 134
    • 66
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 104
    • 54
    • 44
    • 1
    Rat
    Clonality
    • 159
    • 43
    • 1
    Monoclonal
    Conjugate
    • 75
    • 27
    • 23
    • 18
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGAL antibody is un-conjugated
    Application
    • 147
    • 43
    • 37
    • 33
    • 29
    • 29
    • 23
    • 18
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Specificity
    The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    Clone
    M17-4
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product ITGAL Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    ITGAL (Integrin alpha-L (ITGAL))
    Alternative Name
    CD11a (ITGAL Products)
    Background
    The M17/4 monoclonal antibody specifically reacts with mouse CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The M17/4 antibody blocks many of the LFA-1 mediated cell interaction and in vivo it prolongs allograft survival, inhibits the autoimmune response, and reduces graft versus host reactions.
    Gene ID
    16408
    UniProt
    P24063
    Pathways
    Activated T Cell Proliferation, Integrin Complex
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