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BRCA1 antibody (N-Term)

Name: BRCA1 antibody (N-Term)
SKU: ABIN2477707
Price: 570.69 USD
Availability: InStock

BRCA1 Reactivity: Human WB, IF, IHC (p), IP, FACS, IHC (fro) Host: Mouse Monoclonal MS110 unconjugated

(1 reference)

Catalog No. ABIN2477707

Datasheet as PDF

Target See all BRCA1 Antibodies

BRCA1 (Breast Cancer 1 (BRCA1))
Binding Specificity
22

21

15

15

12

12

10

8

7

6

5

5

4

4

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reactivity
190

34

26

3

2

1

1

1
Human
Host
158

37

2
Mouse
Compatible Secondaries
Clonality
162

35
Monoclonal
Conjugate
88

16

9

6

5

5

5

5

5

5

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

1
This BRCA1 antibody is un-conjugated
Application
117

61

42

41

38

35

27

23

22

12

11

10

9

9

3

2

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Characteristics

Purified IgG

Purification

Purified

Immunogen

Recombinant protein corresponding to the N-Terminal region of human BRCA1

Clone

MS110

Isotype

IgG1

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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

1.0 mg/mL
Milner, Wombwell, Eckersley, Barnes, Warwicker, Van Dorp, Rowlinson, Dearden, Hughes, Harbron, Wellings, Hodgson, Womack, Gray, Lau, OConnor, Marsden, Kvist: "Validation of the BRCA1 antibody MS110 and the utility of BRCA1 as a patient selection biomarker in immunohistochemical analysis of breast and ovarian tumours." in: Virchows Archiv : an international journal of pathology, Vol. 462, Issue 3, pp. 269-79, (2013) (PubMed).
Target

BRCA1 (Breast Cancer 1 (BRCA1))

Alternative Name

BRCA1 (BRCA1 Products)

Background

Synonyms: BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN

Gene ID

672

UniProt

P38398

Pathways

Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus