ALDOB antibody
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- Target See all ALDOB Antibodies
- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ALDOB antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Characteristics
- Homo sapiens aldolase B, fructose-bisphosphate (ALDOB)
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human ALDOB (NP_000026) produced in HEK293T cell.
- Clone
- 5D1
- Isotype
- IgG1
- Top Product
- Discover our top product ALDOB Primary Antibody
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- Application Notes
- WB 1:2000, FLOW 1:100,
- Comment
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
- Alternative Name
- ALDOB (ALDOB Products)
- Background
- Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
- Molecular Weight
- 39.3 kDa
- Gene ID
- 229
- NCBI Accession
- NM_000035
- HGNC
- 229
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