Clathrin Heavy Chain (CLTC) (Heavy Chain) antibody
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- Target See all Clathrin Heavy Chain (CLTC) Antibodies
- Clathrin Heavy Chain (CLTC)
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Binding Specificity
- Heavy Chain
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Reactivity
- Human, Mouse, Rat, Cow, Pig
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- Specificity
- The antibody recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa protein involved in receptor-mediated endocytosis.
- Characteristics
- Synonyms: CLTC, CLH17, CLTCL2, KIAA0034, Membrane Vesicle Marker, Clathrin heavy chain onchromosome 17
- Purification
- Ion exchange chromatography
- Purity
- > 95 % (by SDS-PAGE)
- Clone
- BF-06
- Isotype
- IgM
- Top Product
- Discover our top product CLTC Primary Antibody
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anti-Clathrin Heavy Chain (CLTC) antibody
CLTC Reactivity: Human WB, IF, IHC, IP Host: Rabbit Monoclonal unconjugated
anti-Clathrin Heavy Chain (CLTC) antibodyCLTC Reactivity: Human, Mouse, Rat, Cow, Pig WB, ELISA, FACS, IP, ICC Host: Mouse Monoclonal BF-06 unconjugated
anti-Clathrin Heavy Chain (CLTC) antibodyCLTC Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Clathrin Heavy Chain (CLTC) (N-Term) antibodyCLTC Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Monkey, Avian, Chicken, Horse, Rabbit, Cat, Donkey, Goat, Guinea Pig, Hamster, Sheep WB, IF Host: Goat Polyclonal unconjugated
anti-Clathrin Heavy Chain (CLTC) (AA 1019-1048) antibodyCLTC Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB24434 unconjugated
anti-Clathrin Heavy Chain (CLTC) (AA 1617-1630) antibodyCLTC Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Monkey, Xenopus laevis, Chicken, Horse, Rabbit, Bat, Zebrafish (Danio rerio) IHC, IHC (p) Host: Goat Polyclonal unconjugated
anti-Clathrin Heavy Chain (CLTC) (AA 232-340) antibodyCLTC Reactivity: Human WB, ELISA, PLA Host: Mouse Monoclonal 2E5 unconjugated
anti-Clathrin Heavy Chain (CLTC) (AA 851-990) antibodyCLTC Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Clathrin Heavy Chain (CLTC) (AA 401-500) antibodyCLTC Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Clathrin Heavy Chain (CLTC) (AA 232-340) antibodyCLTC Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
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Flow Cytometry: 2-5 μg/mL. Positive control: human blood leukocytes. Immunoprecipitation. Western Blotting. Immunocytochemistry. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
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Store the antibody at 2 - 8 °C. Do not freeze.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- Clathrin Heavy Chain (CLTC)
- Alternative Name
- Clathrin Heavy Chain (CLTC Products)
- Background
- Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.Synonyms: CLH17, CLTC, CLTCL2, Clathrin heavy chain on chromosome 17, KIAA0034, Membrane Vesicle Marker
- Gene ID
- 1213
- UniProt
- Q00610
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