Mycobacterium Tuberculosis Antigen CFP10 (Rv3874) antibody
Reactivity: Mycobacterium tuberculosis
WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target
- Mycobacterium Tuberculosis Antigen CFP10 (Rv3874)
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Reactivity
- Mycobacterium tuberculosis
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- The polyclonal antibody reacts with CFP10 (LHP), a 12,3 kDa antigen encoded by gene Rv3874 of Mycobacterium tuberculosis. The antibody recognizes CFP10 of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis, it reacts also with recombinant antigen produced in Escherichia coli.
- Purification
- Protein-A affinity chromatography.
- Immunogen
- CFP10 (Rv3874) of Mycobacterium tuberculosis
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anti-Mycobacterium Tuberculosis Antigen CFP10 (Rv3874) antibody
Reactivity: Mycobacterium tuberculosis WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Suitable for Western Blotting under Reducing conditions: 0.2-1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4 with 15 mM sodium azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Mycobacterium Tuberculosis Antigen CFP10 (Rv3874)
- Alternative Name
- Cfp10 / EsxB
- Target Type
- Bacteria
- Background
- CFP10 (10 kDa culture filtrate protein) is a low molecular weight protein isolated from Mycobacterium tuberculosis culture filtrates. CFP10 and the 6 kDa early secretory antigen of T cells (ESAT6) are secreted in abundance by Mycobacterium tuberculosis and are frequently recognized by T cells from infected people. The genes encoding these proteins have been deleted from the genome of the vaccine strain Bacille Calmette Guerin (BCG). CFP10 is one of a small number of secreted M. tuberculosis proteins now identified, that appear to play key roles in tuberculosis pathogenesis and in the stimulation of immunity.Synonyms: 10 kDa culture filtrate antigen cfp10, ESAT-6-like protein esxB, MT3988, MTV027.09, Rv3874, Secreted antigenic protein MTSA-10, lhp, mtsA10
- Gene ID
- 886194
- NCBI Accession
- NP_218391
- UniProt
- P0A566
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