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Integrin Alpha2b antibody

CD41 Reactivity: Human FACS, IFA, IHC (f) Host: Mouse Monoclonal P2 unconjugated

Catalog No. ABIN234635

Datasheet as PDF

Target See all Integrin Alpha2b (CD41) Antibodies

Integrin Alpha2b (CD41)
Reactivity
147

31

21

8

7

5

3

3

2

2

2

1

1

1

1

1
Human
Host
100

48

22

1
Mouse
Compatible Secondaries
Clonality
121

44

1
Monoclonal
Conjugate
64

18

14

13

6

4

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Integrin Alpha2b antibody is un-conjugated
Application
126

45

30

26

22

21

13

13

10

9

8

5

2

1

1

1
Flow Cytometry (FACS), Indirect Immunofluorescence Assay (IFA), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity

Reacts with gpIIb in the intact complex with gpIIIa, but not with IIb or IIIa, separately. Inhibits platelet aggregation induced by thrombin, collagen and ADP. The molecular weight of the recognized complex is 135 kDa/95 kDa.

Characteristics

MAb to CD41 gpIIb IIIa, Monoclonal antibody to CD41 gpIIb IIIa

Purification

Protein A Chromatography. Ascites

Immunogen

Human platelets

Clone

P2

Isotype

IgG1

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CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP2 unconjugated

anti-Integrin Alpha2b (CD41) antibody (Biotin)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin

anti-Integrin Alpha2b (CD41) antibody (FITC)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC

anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated

Application Notes

Fluorescence microscopy or flow cytometry: 2 µg/5x106 platelets/test Immunohistochemistry: Working dilution: 1:50 - 1:100. Only suitable on frozen sections or cell smears. Not recommended for use in Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Reconstitute with 1 mL distilled water.

Buffer

Lyophilized from PBS with 1 mg/mL BSA.

Preservative

Without preservative

Handling Advice

Avoid multiple freeze/thaw cycles. The addition of 0.1 % (w/v) sodium azide is recommended for storage of the Reconstituted form for up to one month at 2-8 °C.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.

Storage

4 °C/-20 °C

Storage Comment

Store lyophilized product at 2-8 °C. After reconstitution, aliquot and store at -28 °C.
Target

Integrin Alpha2b (CD41)

Alternative Name

CD41 gpIIb IIIa (CD41 Products)

Pathways

Integrin Complex